Coreceptor use diagnosis

Logistic Regression Classifiers in the Analysis of HIV-1 Use of CCR5 and CXCR4 Coreceptors

The development of HIV coreceptor antagonists—such as maraviroc—has made coreceptor use diagnosis mandatory for each patient in the clinical setting. Technical issues presented by Trofile™, the gold standard phenotypic assay, hindered its use as a …